{"id":153,"date":"2010-11-12T23:54:53","date_gmt":"2010-11-12T23:54:53","guid":{"rendered":"http:\/\/blogs.truman.edu\/mathcs\/?p=153"},"modified":"2010-11-12T23:54:53","modified_gmt":"2010-11-12T23:54:53","slug":"math-bio-colloquium-thursday-nov-18-at-330-in-mg2050","status":"publish","type":"post","link":"https:\/\/blogs.truman.edu\/mathcs\/2010\/11\/12\/math-bio-colloquium-thursday-nov-18-at-330-in-mg2050\/","title":{"rendered":"math bio colloquium Thursday, Nov. 18 at 3:30 in MG2050"},"content":{"rendered":"<p>The mathbio colloquium series continues on Thursday, Nov. 18 at 3:30 p.m. in MG2050. <\/p>\n<p>Dr. Tony Weisstein, Truman Biology Professor, will be speaking on:<\/p>\n<p>&#8220;The Case of the Protective Protein: Using a population genetics simulation in an undergraduate lab course to test hypotheses for the evolution of an HIV resistance allele.&#8221;<\/p>\n<p>Abstract: The delta-32 allele of the human CCR5 chemokine receptor gene helps protect against infection by HIV.  Initial studies proposed that the allele\u2019s current frequency (5\u201314% in many Caucasian populations) might have resulted from relatively recent natural selection by smallpox or the bubonic plague.  In this talk, I will introduce an Excel-based simulation of population genetics that incorporates selection, drift, mutation, and migration.  We will then examine a field-tested lab module in which students use this software to test hypotheses about the evolutionary history of the delta-32 allele.  In the process, students learn the principles behind nonparametric statistics and explore the interactions between stochastic and directional evolutionary forces. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>The mathbio colloquium series continues on Thursday, Nov. 18 at 3:30 p.m. in MG2050. Dr. Tony Weisstein, Truman Biology Professor, will be speaking on: &#8220;The Case of the Protective Protein: Using a population genetics simulation in an undergraduate lab course to test hypotheses for the evolution of an HIV resistance allele.&#8221; Abstract: The delta-32 allele [&hellip;]<\/p>\n","protected":false},"author":185,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-153","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/posts\/153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/users\/185"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/comments?post=153"}],"version-history":[{"count":1,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/posts\/153\/revisions"}],"predecessor-version":[{"id":154,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/posts\/153\/revisions\/154"}],"wp:attachment":[{"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/media?parent=153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/categories?post=153"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.truman.edu\/mathcs\/wp-json\/wp\/v2\/tags?post=153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}